Nitrofuranto inTabletCores （100mg） （Accordingto E.A.Hosny,A.M.S.Ahmed,DrugDev.Ind.Pharm20（9）, 1631–38,1994） 1.Formulation I.Nitrofuranto in..........................................100g Cornstarch[3]..........................................20g Lacto se[8]................................................38g
II.Kollidon30[1]...........................................10g Water.........................................................q.s. III.KollidonCL[1]............................................5g Cornstarch[3]............................................8g Talc[10]......................................................3g Magnesiumstearate[2]...............................1g 2.Manufacturing（Wetgranulation） GranulatemixtureIwithsolutionII,dry,sieve,mixwithIIIandpress. 3.Tabletproperties Weight.................................................180mg Diameter.................................................8mm Form..................................................biconvex Disintegration..........................................5min Dissolution（60min）...................................78% （120min）.................................93%
关键字：nitrofurantoin tablet cores
