NaproxenTablets (250mg) 1.Formulation I.Naproxen(Midas)....................................250g Kollidon90F[1]..........................................6g
II.Kollidon90F[1]..........................................4g CremophorRH40[1]..................................4g Water........................................................41g III.Tabletto se[8]...........................................150g Stearicacid[7]............................................1g AcDiSol[5]................................................10g Magnesiumstearate[2]...............................1g Polyethyleneglycol6000,powder[6]..........10g 2.Manufacturing(Wetgranulation) GranulatemixtureIwithsolutionII,dry,pass througha0.8mmsieve, addIIIandpresswithlowcompressionforce. 3.Tabletproperties Weight.................................................441mg Diameter...............................................12mm Form...................................................biplanar Hardness..................................................47N Disintegration..........................................2min Friability...................................................0.5%
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